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the think tank is very similar to mine. But mine is without the computer compartment. I do know that the carrying area in it is quite deep which is nice.
My 24-70 f2.8 sits upright in it. so does my 100mm macro when carrying it. Just to give you an idea of the depth anyhow.
it's worked fine for both my 70-200 F2.8 (which is about the length of the closed off 100-400mm) and works fine for my 100-400, I've never tryed to put both in at the same time though.
in that i fit, 5DII with 17-35 attached, 7D with 70-200 attached, 70-200 upright, and 2 flashes stacked in their pouches. in side pouch i have chargers, in front pouch my olympus water proof point and shoot.
it holds quite a bit. I've also used the rain bag a few times, and never seen any water get in anywhere.
hope that helps a little.
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