I can't leave the iPad home, because I need something to check my emails and such incase something happens at work while I'm gone.
I'm taking the 50mm f/1.4 because it's the best portrait lens I have. Since I will be visiting family, I think it will be useful. I understand you're issues with primes on vacations, and believe me, I think the same way you do. But it's a pretty small lens and works very well on the 5D2.
I really like the 17-40mm f/4L as well, but I'm much more comfortable with it on my 20D. I still haven't gotten used to it on my 5D2, and 17mm on the APS-C is longer than 24mm on the FF, so I won't be missing much.
The macro lens is a great portrait lens too, and doesn't have to be used specifically for macro. The IS on it is amazing as well. I figured though, I have that range covered by the 24-105mm.
The 70-200mm f/4L IS is really the only one I'm on the fence about. It's a small/light telephoto, but it still takes up space, and is one more thing I need to worry about.
I'm getting a rider on my rental insurance to cover the camera equipment before I leave. It's a no brainer... only ~$1 per $100 covered for a year. I could insure my entire equipment for like $5-6/month.
I won't be taking my 20D, since I won't be hiking. My only worries are those damn sneaky monkeys